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PCE contamination


Roundup MSDS Effective 25jan01

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MONSANTO Company Pages: 1-10
ROUNDUP ORIGINAL[TM] Herbicide Version: 1.2 Effective date: 01/25/2001


MONSANTO Company
Material Safety Data Sheet
Commercial Product

1. PRODUCT AND COMPANY IDENTIFICATION

Product name
         
ROUNDUP ORIGINAL[TM] Herbicide

EPA Reg. No.
         
524-445
Product use
         
Herbicide
Chemical name
         
Not applicable
Synonyms
         
None
Company
         
MONSANTO Company, 800 N. Lindbergh Blvd., St. Louis, MO, 63167 
          Telephone: 800-332-3111, Fax: 314-694-5557

Emergency numbers
          FOR CHEMICAL EMERGENCY, SPILL LEAK, FIRE, EXPOSURE, OR ACCIDENT
Call CHEMTREC- Day or Night 1-800-424-9300 toll free in the continental U.S., Puerto Rico, Canada, or Virgin Islands. For calls originating elsewhere: 703-527-3887 (collect calls accepted).  
          FOR MEDICAL EMERGENCY - Day or Night: 314-694-4000 (collect calls accepted).

2. COMPOSITION/INFORMATION ON INGREDIENTS

Active ingredient
         
Isopropylamine salt of N-(phosphonomethyl)glycine: (Isopropylamine salt of glyphosate

Composition

COMPONENT                              CAS No.    % by weight (approximate)
Isopropylamine salt of glyphosate    38641-94-0            41
Surfactant                           61791-26-2             8
Water                                7732-18-5             51

Trade secret composition.

OSHA Status
         
This product is hazardous according to the OSHA Hazard Communication Standard, 29 CFR 1910.1200.

3. HAZARDS IDENTIFICATION
Emergency overview
Appearance and odour (colour/form/odour):
/ Liquid / Slight

WARNING!
Keep out of reach of children.
CAUSES SUBSTANTIAL BUT TEMPORARY EYE INJURY
HARMFUL IF SWALLOWED
HARMFUL IF INHALED
REFORMULATION IS PROHIBITED
SEE INDIVIDUAL CONTAINER LABEL FOR REPACKAGING LIMITATIONS

Potential health effects

Likely routes of exposure
Skin contact, eye contact
Eye contact short term
Causes temporary eye irritation.
Skin contact short term
Not expected to produce significant adverse effects when recommended use instructions are followed.
Inhalation, short term
Not expected to produce significant adverse effects when recommended use instructions are followed.

Refer to section 11 for toxicological and section 12 for environmental information

4. FIRST AID MEASURES

Eve contact

Immediately flush with plenty of water.
Continue for at least 15 minutes.
If easy to do, remove contact lenses.
If there are persistent symptoms, obtain medical advice.

Skin contact

Wash affected skin with plenty of water.
Wash clothes before re-use.
Take off contaminated clothing, wristwatch, jewellery.

Inhalation

Remove to fresh air.

Ingestion

Immediately offer water to drink.
Do NOT induce vomiting unless directed by medical personnel.
If symptoms occur, get medical attention.

Advice to doctors

This product is not an inhibitor of cholinesterase.

Antidote

Treatment with atropine and oximes is not indicated.

5. FIRE FIGHTING MEASURES

Flash point

Does not flash.

Extinguishing media

Recommended: Water, dry chemical, carbon dioxide (C02), foam

Unusual fire and explosion hazards

None.
Environmental precautions: see section 6.

Hazardous products of combustion

Carbon monoxide (CO), nitrogen oxides (NOx), phosphorus oxides (PxOy)

Fire fighting equipment

Self-contained breathing apparatus.
Equipment should be thoroughly decontaminated after use.

6. ACCIDENTAL RELEASE MEASURES

Personal precautions

Use personal protection recommended in section 8.

Environmental precautions

SMALL QUANTITIES:
Low environmental hazard.
LARGE QUANTITIES:
Minimize spread.
Keep out of drains, sewers, ditches and water ways.

Methods for cleaning up

SMALL QUANTITIES:
Flush spill area with water.
LARGE QUANTITIES:
Absorb in earth, sand or absorbent material.
Dig up heavily contaminated soil.
Collect in containers for disposal.
Refer to section 7 for types of containers.
Flush residues with small quantities of water.
Minimize use of water to prevent environmental contamination.

Refer to section 13 for disposal of spilled material.

7. HANDLING AND STORAGE

Handling

Good industrial practice in housekeeping and personal hygiene should be followed.
Avoid contact with skin and eyes.
When using do not eat, drink or smoke.
Wash hands thoroughly after handling or contact.
Thoroughly clean equipment after use.
Emptied containers retain vapour and product residue.
Observe all labelled safeguards until container is cleaned, reconditioned or destroyed.
Emptied containers retain vapour and product residue.
FOLLOW LABELED WARNINGS EVEN AFTER CONTAINER IS EMPTIED.

Storage

Compatible materials for storage: stainless steel, aluminium, plastic, fiberglass, glass lining
Incompatible materials for storage: galvanized steel, unlined mild steel, see section 10.
Keep out of reach of children.
Keep away from food, drink and animal feed.
Keep only in the original container.
Partial crystallization may occur on prolonged storage below the minimum storage temperature.
If frozen, place in warm room and shake frequently to put back into solution.
Minimum shelf life: 5 years.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Airborne Exposure Limits
Components                            Exposure Guidelines
Isopropylamine salt of glyphosate     No specific occupational exposure limit has been established.
Surfactant                            No specific occupational exposure limit has been established.
Water                                 No specific occupational exposure limit has been established.

Engineering controls

Have eye wash facilities immediately available at locations where eye contact can occur.

Eye protection

If there is potential for contact:

Wear chemical goggles.

Skin protection

If repeated or prolonged contact:

Wear chemical resistant gloves.

Respiratory protection

No special requirement when used as recommended.

When recommended, consult manufacturer of personal protective equipment for the appropriate type of equipment for a given application.

9. PHYSICAL AND CHEMICAL PROPERTIES

These physical data are typical values based on material tested but may vary from sample to sample. Typical values should not be construed as a guaranteed analysis of any specific lot or as specifications for the product.

Form:                             Liquid
Odour:                            Slight
Flash point:                      Does not flash.
Specific gravity:                 1.1655 @ 20C/15.6C
pH:                                4.4 - 5.0
Partition coefficient (log Pow):  < 0.000 (active ingredient)

10. STABILITY AND REACTIVITY

Stability

Stable under normal conditions of handling and storage.

Hazardous decomposition

Thermal decomposition: No data.
Hazardous products of combustion: see section 5.

Materials to avoid/Reactivity

Reacts with bases to liberate heat.
Reacts with galvanized steel or unlined mild steel to produce hydrogen, a highly flammable gas that could explode.

Hazardous polymerization

Does not occur.

11. TOXICOLOGICAL INFORMATION

This section is intended for use by toxicologists and other health professionals. Data obtained on product or on similar products are summarized below. Data obtained on active ingredient are summarized below.

Acute oral toxicity
  Rat, LD50 (limit test):
> 5,000 mg/kg body weight
          Other effects: breathing difficulty, decreased activity, soft stools
          Practically non-toxic.
          FIFRA category IV.
          No mortality.

Acute dermal toxicity
  Rat, LD50 (limit test):
> 5,000 mg/kg body weight
          Target organs/systems : None. 
          Other effects: None. 
          Practically non-toxic. 
          FIFRA category IV. 
          No mortality. 

Acute inhalation toxicity
  Rat, LC50, 4 hours, aerosol:
2.6 mg/L
          Target organs/systems : None.
          Other effects: breathing difficulty, decreased activity, local effects
          Practically non-toxic.
          FIFRA category IV.

Skin irritation
  Rabbit 6 animals, OECD 404 test
          Days to heal: 1 
          Primary Irritation Index (PII): 0.4/8.0 
          Other effects: None. 
          Essentially non irritating. 
          FIFRA category IV. 

Eye irritation
  Rabbit 6 animals , OECD 405 test
          Days to heal: 10 
          Moderate irritation. 
          FIFRA category II. 

Skin sensitization
  Guinea pig, Buehler test Positive incidence: 0 %

EXPERIENCE WITH HUMAN EXPOSURE

Ingestion, short term. case report(s): 
  Gastro-intestinal effects:
irritation, nausea/vomiting, diarrhea

Ingestion, short term:
  Respiratory effects: increased fluid in lungs (lung/pulmonary oedema) 
  Cardiovascular effects:
decreased blood pressure (hypotension)

Similar formulation

Acute oral toxicity

Acute dermal toxicity

Skin irritation

Rabbit 6 animals, OECD 404 test
          Days to heal: 3 
          Primary Irritation Index (PII): 1.0/8.0 
          Slight irritation. 
          FIFRA category IV.

Eye irritation

Rabbit 6 animals , OECD 405 test 
          Days to heal: > 21 
          Other effects: pannus, tissue destruction in eye (necrosis of conjunctivae) 
          Severe irritation. FIFRA category I.

Acute inhalation toxicity

Skin sensitization EXPERIENCE WITH HUMAN EXPOSURE
Eve contact short term. epidemiological
          Note: No cases of irreversible eye effects could be attributed to glyphosate formulations in an extensive epidemiological survey of reported accidental eye contact with these formulations.

N-(phosphonomethyl)glycine

Mutagenicity
  In vitro and in vivo mutagenicity test(s):
          Not mutagenic.

Repeated dose toxicity

Rabbit dermal, 21 days: NOAEL toxicity: > 5,000 mg/kg body weight/day 
          Target organs/systems : None. 
          Other effects: None. 
Rat, oral, 3 months: NOAEL toxicity: > 20,000 mg/kg diet 
          Target organs/systems : None. 
          Other effects: None.

Carcinogenicity

Mouse, oral, 24 months:
          NOEL tumour. > 30,000 mg/kg diet 
          NOAEL toxicity: - 5,000 mg/kg diet 
          Tumours: None. 
          Target organs/systems : liver 
          Other effects: decrease of body weight gain, histopathologic effects

Rat, oral, 24 months:
          NOEL tumour. > 20,000 mg/kg diet 
          NOAEL toxicity: - 8,000 mg/kg diet 
          Tumours: None. 
          Target organs/systems: eyes 
          Other effects: decrease of body weight gain, histopathologic effects 

Toxicity to reproduction/fertility

Rat, oral, 3 generations:
          NOAEL toxicity: > 30 mg/kg body weight
          NOAEL reproduction: > 30 mg/kg body weight
          Target organs/systems in parents: None.
          Other effects in parents: None.
          Target organs/systems in pups: None.
          Other effects in pups: None.

Developmental toxicity/teratogenicity

Rat, oral, 6 - 19 days of gestation:
          NOAEL toxicity: 1,000 mg/kg body weight 
          NOAEL development: 1,000 mg/kg body weight 
          Other effects in mother animal: decrease of body weight gain, decrease of survival 
          Developmental effects: weight loss, post-implantation loss, delayed ossification 
          Effects on offspring only observed with maternal toxicity.

Rabbit oral, 6 - 27 days of gestation:
          NOAEL toxicity: 175 mg/kg body weight 
          NOAEL development: 175 mg/kg body weight 
          Target organs/systems in mother animal: None. 
          Other effects in mother animal: decrease of survival 
          Developmental effects: None.
12. ECOLOGICAL INFORMATION

This section is intended for use by ecotoxicologists and other environmental specialists.

Monsanto has not conducted environmental studies on this product. Data obtained on similar products are summarized below.

Similar formulation

Aquatic toxicity, fish
  Bluegill sunfish (Lepomis macrochirus): 
          Acute toxicity, 96 hours, flowthrough, LC50: 5.8 mg/L 
          moderately toxic
Rainbow trout (Oncorhynchus mykiss): 
          Acute toxicity, 96 hours, flowthrough, LC50: 8.2 mg/L 
          moderately toxic 

Aquatic toxicity, invertebrates
  Water flea (Daphnia magna):
          Acute toxicity, 48 hours, static, EC50: 12.9 mg/L slightly toxic

Aquatic toxicity, algae/aquatic plants
  Green algae (Selenastrum capricornutum): 
          Acute toxicity, 96 hours, static, EC50: 2.6 mg/L moderately toxic

Avian toxicity
  Bobwhite quail (Colinus virginianus): 
          Dietary toxicity, 5 days, LC50: > 5,620 mg/kg diet 
          practically nontoxic
  Mallard duck (Anas platyrhynchos): 
          Dietary toxicity, 5 days, LC50: > 5,620 mg/kg diet 
          practically non-toxic

Arthropod toxicity
  Honey bee (Apis mellifera):
          Oral/contact, 48 hours, LD50: > 100 g/bee 
          practically non-toxic

Soil organism toxicity, invertebrates
  Earthworm (Eisenia foetida): 
          Acute toxicity, 14 days, LC50: > 5,000 mg/kg dry soil practically non-toxic

N-(phosphomethyl)glycine: (glyphosate)

Bioaccumulation
  Bluegill sunfish (Lepomis macrochirus): 
          Whole fish: BCF: < 1 
          No significant bioaccumulation is expected.

Dissipation
  Soil, field: 
          Half life: 2 - 174 days 
          Koc: 884 - 60,000 L/kg
          Binds strongly to soil.
Water, aerobic: 
          Half life: < 7 days

Identical product without green dye

Biodegradation
  Zahn-Wellens test: 
          Degradation: 80 "/o within 28 days 
          Inherently biodegradable.

13. DISPOSAL CONSIDERATIONS

Product
          Dispose of as hazardous industrial waste.
          Recycle if appropriate facilities/equipment available.
          Burn in special, controlled high temperature incinerator.
          Keep out of drains, sewers, ditches and water ways.
          Follow all local/regional/national regulations.

Container
          Triple rinse empty containers.
          Pour rinse water into spray tank.
          Store for collection by approved waste disposal service.
          Dispose of as hazardous industrial waste.
          Do NOT re-use containers.
          Follow all local/regional/national regulations.

14. TRANSPORT INFORMATION

The data provided in this section is for information only. Please apply the appropriate regulations to properly classify your shipment for transportation.

Not hazardous under the applicable DOT, ICAO/IATA, IMO, TDG and Mexican regulations.

15. REGULATORY INFORMATION

TSCA Inventory
          All components are on the US EPA's TSCA Inventory
SARA Title III Rules
  Section 311/312 Hazard Categories
          Immediate
  Section 302 Extremely Hazardous Substances 
          Not applicable.
  Section 313 Toxic Chemical(s) 
          Not applicable.

CERCLA Reportable quantity
          Not applicable.

16. OTHER INFORMATION

The information given here is not necessarily exhaustive but is representative of relevant, reliable data. For more information refer to product label. Please consult Monsanto if further information is needed. Follow all local/regional/national regulations. In this document the British spelling was applied. All trademarks herein are trademarks of Monsanto Company or its subsidiaries.

Full denomination of most frequently used acronyms. BCF (Bioconcentration Factor), BOD (Biochemical Oxygen Demand), COD

(Chemical Oxygen Demand), EC50 (50/ effect concentration), ED50 (50/ effect dose), I.M. (intramuscular), I.P. (intraperitoneal), TV. (intravenous), Koc (Soil adsorption coefficient), LC50 (50/ lethality concentration), LD50 (50/ lethality dose), LDLo (Lower limit of lethal dosage), LEE (Lower Explosion Limit), LOAEC (Lowest Observed Adverse Effect Concentration), LOAEL (Lowest Observed Adverse Effect Level), LOEC (Lowest Observed Effect Concentration), LOLL (Lowest Observed Effect Level), MEL (Maximum Exposure limit), MTD (Maximum Tolerated Dose), NOAEC (No Observed Adverse Effect Concentration), NOAEL (No Observed Adverse Effect Level), NOEC (No Observed Effect Concentration), NOEL (No Observed Effect Level), OEL (Occupational Exposure Limit), PEL (Permissible Exposure Limit), PII (Primary Irritation Index), Pow (Partition coefficient n-octanol/water), S.C. (subcutaneous), STEL (Shot-Term Exposure Limit), TLV-C (Threshold Limit Value-Ceiling), TLV-TWA (Threshold Limit Value - Time Weighted Average), UEL (Upper Explosion Limit)

This Material Safety Data Sheet (MSDS) serves different purposes than and DOES NOT REPLACE OR MODIFY THE EPA-APPROVED PRODUCT LABELING (attached to and accompanying the product container). This MSDS provides important health, safety, and environmental information for employers, employees, emergency responders and others handling large quantities of the product in activities generally other than product use, while the labeling provides that information specifically for product use in the ordinary course. Use, storage and disposal of pesticide products are regulated by the EPA under the authority of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) through the product labeling, and all necessary and appropriate precautionary, use, storage, and disposal information is set forth on that labeling. It is a violation of federal law to use a pesticide product in an manner not prescribed on the EPA-approved label.

Although the information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed to be correct as of the date hereof, MONSANTO Company makes no representations as to the completeness or accuracy thereof. Information is supplied upon the condition that the persons receiving same will make their own determination as to its suitability for the purposes prior to use. In no event will MONSANTO Company be responsible for damages of any nature whatsoever resulting from the use of or reliance upon information. NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER NATURE ARE MADE HEREUNDER WITH RESPECT TO INFORMATION OR TO THE PRODUCT TO WHICH INFORMATION REFERS.

 

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